Testing for Tuberculosis (2024)

Why get tested

Getting tested and treated for TB can protect yourself, your family and friends, and your community.

You may need a TB test if you have:

  • Symptoms of TB disease
    • Spent time with someone who has active TB disease
      • Factors that put you at higher risk of developing active TB disease
        • Employment, school, travel, or immigration health screening requirements

          You may need a TB test even if you do not feel sick. TB germs can live in your body for years without making you feel sick. This is called inactive TB. People with inactive TB do not feel sick and cannot spread TB germs to others.

          Keep Reading:Treating Tuberculosis

          Who should be tested

          If you are at higher risk of being infected with TB germs, you should get tested.

          You have a higher risk of being exposed to TB germs if you:

          • Were born in or frequently travel to countries where TB is common, including some countries in Asia, Africa, and Latin America
            • Live or used to live in large group settings where TB is more common, such as homeless shelters, prisons, or jails
              • Recently spent time with someone who has active TB disease
                • Work in places where TB is more likely to spread, such as hospitals, homeless shelters, correctional facilities, and nursing homes

                  Some people who have inactive TB never develop TB disease, and others with inactive TB develop active TB disease months or even years later when their immune system can no longer keep the TB germs from multiplying and growing in the body.

                  Anyone can get TB, but some people who have inactive TB are more likely to develop TB disease than others.

                  You have a higher risk of developing TB disease once infected if you:

                  • Have a weaker immune system because of certain medications or health conditions such as diabetes, cancer, or HIV
                    • Became infected with TB germs in the last two years
                      • Are a baby or young child, especially under five years of age
                        • Inject illegal drugs
                          • Are sick with other diseases that weaken the immune system
                            • Are elderly
                              • Were not treated correctly for TB in the past

                                TB tests are generally not needed for people with a low risk of infection with TB germs.

                                Keep Reading:Tuberculosis Risk Factors

                                Types of tests

                                There are two types of tests for TB infection: the TB blood test and the TB skin test. Ask your health care provider which TB test is best for you.

                                TB blood test

                                TB blood tests (also called interferon-gamma release assays or IGRAs) use a blood sample to find out if you are infected with TB germs. The tests measure how your immune system reacts when a small amount of your blood is mixed with TB proteins.

                                Tell your health care provider if you received a TB vaccine‎‎

                                Many people born outside the United States have received the TB vaccine (also known as Bacille Calmette-Guérin or BCG).

                                TB blood tests are the preferred test for people who have received the TB vaccine. Unlike the TB skin test, TB blood tests are not affected by BCG vaccination.

                                Keep Reading:Testing for Tuberculosis: Blood Test

                                TB skin test

                                For the TB skin test, a health care provider uses a small needle to put some testing material under the skin. You will need to return to your health care provider in two to three days to see if there is a reaction.

                                Keep Reading:Testing for Tuberculosis: Skin Test

                                Other tests may be needed

                                Your health care provider will do other tests to determine if you have inactive TB or active TB disease if you have a:

                                • Positive TB blood test or TB skin test result
                                  • Negative TB blood test or TB skin test result, but you have symptoms of active TB disease

                                    These tests may include a chest x-ray, and a test of the sputum (phlegm) you cough up.

                                    Keep Reading:Diagnosing Tuberculosis

                                    How to get tested

                                    You can get tested for TB at the health department or at your health care provider's office. Your health care provider will choose the TB test that is best for you. Public and private health care plans may cover TB testing costs.

                                    Finding a test location‎

                                    Contact your state or local TB program about getting tested for TB.

                                    State TB Programs

                                    Understanding TB blood test or TB skin test results

                                    A positive test result for TB infection means you have TB germs in your body. Your health care provider will do other tests to determine if you have inactive TB or active TB disease. These tests may include a chest x-ray, and a test of the sputum (phlegm) you cough up.

                                    A negative test result for TB infection means inactive TB or active TB disease is unlikely, but your health care provider may do more tests, especially if:

                                    • You have symptoms of active TB disease, like coughing, chest pain, fever, weight loss, or tiredness.
                                      • You have HIV.
                                        • You were recently exposed to TB germs.

                                          Keep Reading:Diagnosing Tuberculosis

                                          What to do if you've tested positive

                                          If your TB blood test or TB skin test is positive, you have TB germs in your body. Your health care provider will do other tests to determine if you have inactive TB or active TB disease.

                                          Keep a record of your positive test result‎

                                          Once you have a positive TB blood test or TB skin test result, you may still have a positive test result on future TB tests. This includes even after you finish taking all of your TB medicine for inactive TB or active TB disease.

                                          Ask your health care provider for a written record of your positive TB test result. This will be helpful if you are asked to have another TB test in the future.

                                          Keep Reading:Diagnosing Tuberculosis

                                          Resources

                                          What You Need to Know About Tuberculosis Fact Sheet

                                          Use this fact sheet to learn basic information about tuberculosis (TB).

                                          Questions and Answers About Tuberculosis Booklet

                                          Questions and Answers About TB has information on inactive TB and TB disease.

                                          What You Need to Know About the TB Skin Test Fact Sheet

                                          Learn what to expect when getting a TB skin test.

                                          Testing for Tuberculosis (2024)

                                          FAQs

                                          What test can confirm tuberculosis? ›

                                          The tuberculosis (TB) blood test, also called an Interferon Gamma Release Assay or IGRA, is a way to find out if you have TB germs in your body. The TB blood test can be done instead of a TB skin test (Mantoux). There are two kinds of TB blood tests: QuantiFERON®-TB.

                                          What is the most accurate way to test for TB? ›

                                          QFT has been shown to be more accurate than the TST in identifying people who may have latent TB infection. A meta-analysis calculated a pooled sensitivity for TST at 70%,4 (23 of 25 studies in developed countries) and a pooled sensitivity for QFT at 84% (13 studies in developed countries).

                                          What is the gold standard for TB test? ›

                                          Culture is the gold standard microbiologic test for the diagnosis of TB disease.

                                          How can you tell the results of a TB test? ›

                                          Your health care provider MUST check your arm 2 or 3 days after the TB skin test, even if your arm looks OK to you. If you have a reaction to the test, it will look like a raised bump. Your health care provider will measure the size of the reaction. If there is a bump, it will go away in a few weeks.

                                          How to check tuberculosis at home? ›

                                          Check if you have tuberculosis (TB)
                                          1. a cough that lasts more than 3 weeks – you may cough up mucus (phlegm) or mucus with blood in it.
                                          2. feeling tired or exhausted.
                                          3. a high temperature or night sweats.
                                          4. loss of appetite.
                                          5. weight loss.
                                          6. feeling generally unwell.

                                          What is the gold test for TB? ›

                                          QuantiFERON-TB Gold (QFT) is a simple blood test that aids in the detection of Mycobacterium tuberculosis, the bacteria which causes tuberculosis (TB).

                                          Can TB test be incorrect? ›

                                          Test accuracy

                                          Some persons may have a positive result from a TB skin test even though they are not infected with TB bacteria. The causes of these false-positive results may include, but are not limited to, the following: Previous TB vaccination with the bacille Calmette Guérin (BCG) vaccine.

                                          What are four ways to test for TB? ›

                                          A diagnosis of latent TB infection is made if the person has a positive result from a TB blood test or TB skin test and a medical evaluation does not indicate TB disease. TB disease is diagnosed by medical history, physical examination, chest x-ray, and other laboratory tests, including culture.

                                          How to know if a TB test is positive? ›

                                          If you have a raised, hard bump or there's swelling on your arm, you have a positive test. That means TB germs are in your body. But it doesn't always mean you have active tuberculosis disease.

                                          What is the best method to diagnose TB? ›

                                          A health care provider may diagnose you with inactive TB or active TB disease based on your:
                                          • Medical history.
                                          • Physical examination.
                                          • Test for TB infection (TB blood test or TB skin test)
                                          • Chest x-ray.
                                          • Laboratory tests to see if TB germs are present (sputum smear and culture)
                                          • Laboratory tests for drug resistance.
                                          Apr 22, 2024

                                          What is confirmatory test for tuberculosis? ›

                                          People diagnosed with TB using rapid molecular tests recommended by WHO (1), lateral flow urine lipoarabinomannan (LF-LAM) assays, sputum smear microscopy or culture are defined as “bacteriologically confirmed” cases of TB (2).

                                          What does it mean if a QuantiFERON test is positive? ›

                                          You have a positive Tuberculin Skin Test (TST) or QuantiFERON blood test: what does this mean? If your TST (Mantoux) or Quantiferon blood test was found to be positive, this means you have a latent TB infection, but usually not the active disease.

                                          What not to do after a TB test? ›

                                          After the test, you should avoid using bandages, putting on lotion, or scratching the test area because it may affect the results. You can wash the area with water, but do not wipe or scrub. If the area itches, put an ice cube or cold cloth on it.

                                          What is a positive number for a TB test? ›

                                          A 10 mm induration may also be considered positive in children under age 4 or people who use injected drugs. An induration of 15 mm or more is considered positive in anyone, even people who don't think they've been exposed to TB.

                                          What is a negative TB test supposed to look like? ›

                                          The test is “negative” if there is no bump (or only a very small bump) at the spot where the fluid was injected. A negative TB skin test usually means that you don't have TB. In some situations, you may need to have another TB skin test later.

                                          How do you confirm if you have TB? ›

                                          A health care provider may diagnose you with inactive TB or active TB disease based on your:
                                          1. Medical history.
                                          2. Physical examination.
                                          3. Test for TB infection (TB blood test or TB skin test)
                                          4. Chest x-ray.
                                          5. Laboratory tests to see if TB germs are present (sputum smear and culture)
                                          6. Laboratory tests for drug resistance.
                                          Apr 22, 2024

                                          What is the most common screening test for tuberculosis? ›

                                          You will have either be a TB skin test or a TB blood test, depending on your health and medical history. TB skin tests are used more often, but blood tests for TB are becoming more common. For a TB skin test (also called a Mantoux tuberculin skin test), you will need two visits to complete the test.

                                          What type of test list for TB? ›

                                          There are currently two methods for detecting tuberculosis infection: The Mantoux tuberculin skin test (TST) and an Interferon Gamma Release Assay (IGRA) blood test. Patients must be carefully assessed for risk factors PRIOR to administration of either test.

                                          Can a CBC detect tuberculosis? ›

                                          No they dont show up in CBC as confirmatory test.

                                          References

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